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49ers vs. Seahawks odds, lines and spreads: Thursday Night Football picks, NFL predictions from computer models


The San Francisco 49ers visit division rivals the Seattle Seahawks in Thursday Night Football as they try to clinch the NFC West with their seventh straight victory. San Francisco (9-4), who beat Seattle 27-7 at home in Week 2, leads the Seahawks (7-6) by two games with four games remaining. The 49ers traveled to Tampa Bay last Sunday, trailing 35-7, behind the rookie quarterback’s block behind his Purdy, who made his first career start due to injuries to Tralance (ankle) and Jimmy Garoppolo (foot). Victory. Seattle suffered his 30-24 loss at home against Carolina, his third loss in four contests.

Kickoff from Lumenfield is set for 8:15 PM ET. The Caesars Sportsbook’s latest 49ers vs. Seahawks odds show San Francisco as the 3.5-point favourite, with an over/under total score of 43.5. Before making the Seahawks vs. 49ers pick, you should check out the NFL predictions and betting advice from SportsLine’s Advanced Computer Model.

This model, which simulates every NFL game 10,000 times, has earned over $7,000 for a $100 player on the highest-rated NFL pick since its inception. This model enters Week 15 of the 2022 NFL season with an incredible 157-113 run in the highest-rated NFL picks dating back to the 2017 season. The model has also gone blazing 21-5 in straight-up NFL picks over the past two weeks.

The model has ranked in NFLPickWatch’s top 10 NFL picks over the past six years, beating out over 94% of CBS Sports Football Pick’em players four times during that period. Anyone who followed it is on top.

The model now has its sights set on the 49ers vs. Seahawks, locking that pick and Thursday night football predictions. Visit SportsLine today to see our model recommendations. Here are the Seahawks vs. 49ers NFL odds and betting lines:

  • 49ers vs. Seahawks spread: San Francisco -3.5
  • 49ers vs. Seahawks Over/Under: 43.5 points
  • 49ers vs. Seahawks moneyline: San Francisco -190, Seattle +158
  • SF: 49ers are 2-8-1 against the spread in last 11 games in Seattle
  • SEA: Seahawks are 8-2-2 ATS in last 12 Thursday contests
  • 49ers vs. Seahawks Picks: Here’s Our Picks

Featured games | | Seattle Seahawks vs. San Francisco 49ers

Why the 49ers Can Cover

Purdy, the 262nd final pick in this year’s NFL Draft, has completed 70.7% of his pass attempts with four touchdowns and one interception since replacing Jimmy Garoppolo (toe) in Week 13. Mark is the first quarterback since Bulger in 2002 to record his first career passer rating of at least 130, his toss twice, and his rushing score in his first career start. Purdy, who is dealing with an oblique/rib injury, will not have Debo his Samuel (ankle/knee) free in his TNF, but double threat Christian his McCaffrey joining the backfield. increase.

Acquired from Carolina in October, McCaffrey threw for 119 yards against Tampa Bay, his first 100-yard rushing performance since Week 3 with the Panthers. The 26-year-old ran for a touchdown, 34 yards where he had two catches and he scored one, and in his seven games with the 49ers he had three rushes and he had three runs. Achieved a receive TD. Wide his receiver Brandon Ayuk scored his receptions for his seventh touchdown, a career-high in San Francisco. Find out which team to choose here.

Why the Seahawks Can Cover

Seattle may be in the doldrums, but their last three losses and five of their six losses this season came from one possession. Breaking up with Russell Wilson during the offseason proved to be the right decision. Former franchise his quarterback Russell Wilson has a passer rating of 85, which ranks him 27th in the NFL. Just two years younger than Wilson, the 32-year-old Smith has threw at least two touchdowns on his pass in seven straight games, and this year he’s 13 out of 13 appearances. Throwing 11 times.

Smith ranks fourth in the league with 25 TD tosses, sixth in passing yards with 3,433, and ranks sixth in scoring (26.3 points). West Virginia’s product has an excellent pair of receivers targeting Tyler Rocket and his DK Metcalf, both on pace to post his 1,000-yard season. The Rockets led the Seahawks with eight touchdowns for 896 yards and 71 receptions, while Metcalf had a team-high 72 catches for 869 yards and six points. Please look.

How to make a 49ers vs. Seahawks pick in TNF

SportsLine’s model is below the points total, claiming a total of 43 points. The model also shows that he hits one side of the spread more than 50% of the time. TNF picks for this model can only be found on SportsLine.

So who will win Seahawks vs. 49ers in Thursday Night Football, and which side of the spread will hit more than 50% of the time? From the model, see and find out which side of the Seahawks vs. 49ers spread you need to jump.





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